Downstream Bioprocessing Intern/Co-op

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Career Programs

Job Sub Function:

Non-LDP Intern/Co-Op

Job Category:

Career Program

All Job Posting Locations:

Malvern, Pennsylvania, United States of America

Job Description:

Johnson & Johnson Innovative Medicine is recruiting for a Spring 2026 Co-Op in Downstream Bioprocessing, located in Malvern, PA.

Research & Development Co-Op Overview:

J&J R&D encompasses the development of sophisticated materials, process improvements, risk management and mechanical testing through the development process across all sectors including Pharmaceutical, Medical Device, Consumer and Corporate/Enterprise.

We offer a fast-paced cross-functional, technologically advanced, corporate environment, passionate about developing individual engineering and scientific skills. You will have the opportunity to learn about anatomy, disease states, deformities and the surgical procedure/products used to address these conditions.

Life as an R&D Co-Op:

The R&D Co-Op program provides each student with real-life hands-on experience, coaching and mentoring, networking opportunities, as well as the opportunity to meet people from various schools throughout the country. Each Co-Op will be assigned to a single function with a specific project for the 6-month term.

The typical Co-Op term is from Jan 2026– Jun 2026.

Key Responsibilities:

The TDS Proteins Development API organization is seeking a candidate interested in protein process development. Various chromatography methods are utilized in the downstream sphere to purify protein molecules from process impurities and aggregates. Assessing the impact of product- and process-related impurities such as high molecular weight species (HMWS) and host cell impurities, respectively, on final drug substance (DS) stability is crucial for development of potent biopharmaceutical products and for establishing downstream bioprocesses to effectively balance yield with product quality. In this role, the Co-Op will...

• Study the impact of variable levels of HMW content and co-associated host impurities on stability-indicating attributes across two model antibody products.
• Purify biopharmaceutical products to achieve variable levels of HMW content through targeted control of cation exchange (CEX) and multi-modal anion exchange (MMAEX) process operating conditions.
• Evaluate stability-indicating quality attributes of drug substance across different HMWS experimental test conditions, and perform in-depth data analysis to communicate key results.
• Contribute to the expansion of experimental framework examining HMWS content impacts on product stability to one or more additional antibody products (time permitting).
• Analyze and interpret experimental results using analytical and statistical techniques. Actively participate in weekly meetings with internal and external collaborators.
• Participate in technical discussions on design of experiments to fill gaps in knowledge.
• Maintain a laboratory notebook and other technical documents according to required guidelines.
• Provide other project support as needed.

Qualifications

Education:

• Biochemistry, Chemical Engineering, Biological Engineering, and related majors are preferred.
• Candidates must be actively enrolled in an accredited University for the duration of a co-op assignment pursuing a Bachelor’s or equivalent experience, Master’s, or PhD degree or equivalent experience. For students pursuing their Bachelor's degree or equivalent experience, Juniors or Seniors are preferred.
• Minimum GPA of 2.8 is required.
• Completion of Undergraduate Freshmen year at an accredited University is required.

Experience and Skills:

Required:

• Students with w bachelors degree or higher in chemical/biochemical engineering or related biological science discipline with experience in technical writing and documentation.
• Candidate must be legally authorized to work in the U.S. and must not require sponsorship for employment visa status now or in the future (e.g., FI, H1-B status)
• Ability to demonstrate strong analytical and quantitative skills is required
• Excellent communication, presentation, and leadership skills are preferred
• Ability to balance multiple projects and initiatives while performing results
• Must be a self-starter works independently while supplying to the team goals
• Proven leadership/participation with campus programs and/or community service activities is desired

Preferred:

• Students with basic laboratory skills and experience in research, experimental design & execution, and data analysis preferred.
• Students with prior hands-on experience in biopharmaceutical purification processes including chromatography, filtration (depth filtration, membrane filtration, UF/DF, or SPTFF) and other relevant lab techniques.
• Students with prior experience working with AKTA chromatography systems and familiarity with Unicorn software.
• Students with previous experience working with antibodies or other biologically-derived protein therapeutics.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. 

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation,  external applicants please contact us via https://www.jnj.com/contact-us/careers . Internal employees contact AskGS to be directed to your accommodation resource.