Preclinical Research Co-op

Orna Therapeutics, Inc. is a Watertown-based biotechnology startup on a mission to create therapies for diseases inaccessible to existing approaches. Built on novel circular RNA technology developed at MIT, Orna is leading the next wave of RNA therapeutics with our best-in-class expression and delivery platform.

We are seeking an exceptional Co-op to join our preclinical bioanalysis team. This team member will learn and contribute to multiple aspects of our in vivo novel panCAR programs. The position will report to a Senior Scientist in the bioanalysis team. An ideal candidate will possess strong oral and written communication, demonstrate excellent collaboration and interpersonal skills, and be curious and self-motivated.

Responsibilities

• Perform analyte extraction techniques (e.g., immunoprecipitation, SPE) and sample preparation from complex matrices.
• Assist with development and optimization of LC-MS/MS methods for the quantitative analysis of small molecules and proteins in relevant biological matrices (e.g., plasma, tissues).
• Troubleshoot and maintain instrumentation to ensure robustness, sensitivity, and reproducibility.
• Keep accurate records and document experimental results in electronic laboratory notebooks.
• Prepare presentations and present results at internal meetings.
• Participate in solving technical problems in a logical and rationale manner.

Qualifications

• Undergraduate or graduate student in analytical chemistry, biochemistry, biotechnology or a related field.
• Familiarity with the principles of HPLC and mass spectrometry is a plus.
• Detail oriented and self-motivated, willingness to learn new MS-based technologies.
• Effective written and oral communication skills.

Why work at Orna?

In addition to working alongside bright and hardworking colleagues, you’ll have the opportunity to experience an array of benefits throughout your time with us, including: 

• Invitations to company outings and social events
• Opportunities to meet with our Executive and Management teams
• Participation in department specific and organization wide meetings and trainings
• Various personal and professional development opportunities
• Transportation or parking expenses
• Company swag
• Coverage under MA Sick Time and MA Paid Family and Medical Leave
• Paid holidays, except company shutdowns, and two days of vacation, eligible after a 90-day probationary period

Equal Employment Opportunity Statement

Individuals seeking employment at Orna Therapeutics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation. 

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